Traditional drug delivery systems (eg. oral or intravascular delivery), the drug or therapeutic molecules are distributed throughout the whole body by the systemic blood circulation. A majority of molecules do not reach their targets and subsequently, stay in the body causing side effects. Our locked nucleic acid (LNA) enforced super Nano delivery targeting module could efficiently deliver the therapeutic molecules to the targeting organ. So, our locked nucleic acid (LNA) enforced super Nano delivery system has several significant advantage.  For example, due to their small size nanoparticles are able to avoid opsonization by MPS and remain in the blood circulation for a longer duration of time as compared to microparticles and other traditional drug delivery systems